The only way this will work as of now (at least in the US, I’m unsure how extensions may work on a third party App Store with the newer EU regulations) is if you use safari only. iOS allows for safari extensions from the App Store which already have things like ad blockers, but they definitely do not run within any third party apps. The code is certainly likely to be open source, but I definitely don’t see chrome/brave integrating it as part of their app bundle. Perhaps Firefox? In any case it’s up to each browser vendor to provide their own ad blocking system. For complete system wide adblocking on iOS you pretty much need a VPN.

It’s going to be safari only. There’s no API on iOS for system wide blocking unless it’s a third party VPN server filtering network requests.

Not surprised, Apple hates devs anyway. Like I said, I used NextDNS to filter internet traffic and used Proton VPN for pirating/hiding my IP/usual shit. I'm on Graphene now so I'm not invested anyway, but maybe I would've forced myself to use Safari if uBlock was available for it.

Don't expect to block stuff from Google while using Chrome. Google is [one of] the biggest advertising companies

No.

The “all browsers are iOS reskin” thing is browsers must use WebKit for JavaScript and rendering, which are the two biggest parts of a browser. WebKit is a library of code distributed as part of the iOS SDK. However, Safari adds more on top of WebKit, including its plugin API. Installing plugins into iOS Safari wont affect anything just using WebKit because they aren’t using the Safari plugins code.

In theory Firefox could implement its own plugins system for iOS, but it would more limited than the normal Firefox plugin system for other devices, and also they might run into policy issues with Apple (this policy about 3rd party browsers is part of a broader policy against side loading, which has in the past prevented things like emulators and programming apps into the App Store. They have recently started loosening up on their anti-side loading policies, however).

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Waiting on the day Firefox extensions support the iOS app.

Can confirm, have used macOS on both the old Intel and new M-series chips, and Firefox with uBO works well.

Btw Adguard collects your data. Check their privacy policy. The moment I knew this, I moved to mullvad DNS but nowadays it is not stable. (I use private DNS for system-wide adblocking)

I don’t use their DNS feature, just the adblocking.

Will never happen unfortunately